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	Provedor de dados BJMBR (3) Autor Lopes,O.U. (3) Campos,R.R. (2) Andreatta-Van Leyen,S. (1) Araujo,G.C. (1) Bergamaschi,C.T. (1) Biancardi,V.C. (1) Cravo,S.L. (1) Guertzenstein,P.G. (1) Lacerda,J.E.C. (1) Russo,A.K. (1) Tolentino-Silva,F.P. (1) Mais... Palavra-chave Breathing pattern (1) Cardiorespiratory control (1) Conscious rats (1) GABA (1) Kynurenic acid (1) L-NAME hypertension (1) Nitric oxide synthase blockade (1) RVLM (1) Rat (1) Sympathetic nervous system (1) Total peripheral resistance (1) Vasomotor tone (1) Ventral surface of the medulla (1) Ventrolateral medulla (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2007 (1) 2003 (1) 1998 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Cardiovascular responses to microinjections of GABA or anesthetics into the rostral ventrolateral medulla of conscious and anesthetized rats BJMBR Lacerda,J.E.C.; Campos,R.R.; Araujo,G.C.; Andreatta-Van Leyen,S.; Lopes,O.U.; Guertzenstein,P.G.. The rostral ventrolateral medulla (RVLM) contains neurons involved in tonic and reflex control of arterial pressure. We describe the effects of gamma-aminobutyric acid (GABA) and anesthetics injected into the RVLM of conscious and urethane (1.2 g/kg, iv) anesthetized Wistar rats (300-350 g). In conscious rats, bilateral microinjection of GABA (50 nmol/200 nl) induced a small but significant decrease in blood pressure (from 130 ± 3.6 to 110 ± 5.6 mmHg, N = 7). A similar response was observed with sodium pentobarbital microinjection (24 nmol/200 nl). However, in the same animals, the fall in blood pressure induced by GABA (from 121 ± 8.9 to 76 ± 8.8 mmHg, N = 7) or pentobarbital (from 118 ± 4.5 to 57 ± 11.3 mmHg, N = 6) was significantly increased after... Tipo: Info:eu-repo/semantics/article Palavras-chave: Vasomotor tone; Ventrolateral medulla; RVLM; GABA; Conscious rats. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900019 Respiratory effects of kynurenic acid microinjected into the ventromedullary surface of the rat BJMBR Tolentino-Silva,F.P.; Russo,A.K.; Cravo,S.L.; Lopes,O.U.. Several studies demonstrate that, within the ventral medullary surface (VMS), excitatory amino acids are necessary components of the neural circuits involved in the tonic and reflex control of respiration and circulation. In the present study we investigated the cardiorespiratory effects of unilateral microinjections of the broad spectrum glutamate antagonist kynurenic acid (2 nmol/200 nl) along the VMS of urethane-anesthetized rats. Within the VMS only one region was responsive to this drug. This area includes most of the intermediate respiratory area, partially overlapping the rostral ventrolateral medulla (IA/RVL). When microinjected into the IA/RVL, kynurenic acid produced a respiratory depression, without changes in mean arterial pressure or heart... Tipo: Info:eu-repo/semantics/other Palavras-chave: Ventral surface of the medulla; Breathing pattern; Cardiorespiratory control; Kynurenic acid; Rat. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001000016 Sympathetic activation in rats with L-NAME-induced hypertension BJMBR Biancardi,V.C.; Bergamaschi,C.T.; Lopes,O.U.; Campos,R.R.. We evaluated the hemodynamic pattern and the contribution of the sympathetic nervous system in conscious and anesthetized (1.4 g/kg urethane, iv) Wistar rats with L-NAME-induced hypertension (20 mg/kg daily). The basal hemodynamic profile was similar for hypertensive animals, conscious (N = 12) or anesthetized (N = 12) treated with L-NAME for 2 or 7 days: increase of total peripheral resistance associated with a decrease of cardiac output (CO) compared to normotensive animals, conscious (N = 14) or anesthetized (N = 14). Sympathetic blockade with hexamethonium essentially caused a decrease in total peripheral resistance in hypertensive animals (conscious, 2 days: from (means ± SEM) 2.47 ± 0.08 to 2.14 ± 0.07; conscious, 7 days: from 2.85 ± 0.13 to 2.07 ±... Tipo: Info:eu-repo/semantics/article Palavras-chave: L-NAME hypertension; Sympathetic nervous system; Nitric oxide synthase blockade; Total peripheral resistance. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000300016 Registros recuperados: 3 Primeira ... 1 ... Última

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